|Home > About Genox and JaICA
As an organization dedicated to health, we will strive to ensure the health of people worldwide.
We will contribute to promoting the health of all people worldwide.
|We will provide safe, high-quality, and valuable products and services based on our daily
research and efforts.
|We will conduct fair transactions, respect ethics, and comply with laws and regulations in order
to be a reliable enterprise.
|We will perform sound management and develop as an enterprise contributing to health promotion.
|We will effectively utilize resources and contribute to creating a healthy society
while assuring harmony with the local community and natural environment.
|We will always endeavor to improve ourselves and perform our tasks to the best of our ability and
will assure full responsibility.
|We will share the philosophy "health contribution" and our objectives and explore the future
with a spirit of creation and innovation.
|Company name: Genox Corporation
Representative: Seiichi Ohi
Street address: 21151 S. Western Ave. STE#103, Torrance, CA90501, USA
Genox Corporation, located in Torrance, California, is a subsidiary of NIKKEN SEIL, Co. Ltd., Japan.
The products offered by us are made in Japan either by our parent company, at the Japan Institute for the Control of Aging (JaICA),
a division of Nikken SEIL Co., Ltd. or by our business partner, at the Life Science Products Division of the Nippon Oils and Fats
Corporation, Japan. Genox is the distributor of these products for users in North and South America.
Our main line of business is in the Development of Novel Oxidative Stress Biomarkers for the Advancement of Basic and
Applied Research Related to the Mechanism of Aging and to Understand the Role of Oxidative Stress in Biology and Medicine.
Our main objective is to take advantage of the remarkable progress that has been made in this relatively new scientific field,
and to utilize this knowledge base for the development of:
*Cost-effective methods of assessing oxidative stress and its determinants in biological systems
*Methods to measure oxidative stress that can be applied to the improvement of the functionality of processed foods,
agricultural produce, dietary nutrient supplements, and pet food formulations
The company was organized in October 1991 as a Minnesota Corporation by a small group of investors, along with
Dr. Richard G. Cutler. Dr. Cutler is a well-known scientist in the field of molecular gerontology.
Prior to founding Genox, Dr. Cutler spent 18 years as a research chemist at the National Institute on Aging (NIA) of the National Institutes of Health (NIH). In 1994 Genox moved its business location from Minneapolis, MN, to Baltimore, MD, and in 2018
sunsequently moved to Torrance, CA.
During the past decade Genox has served the scientific community by providing to researchers products and analytical
testing services for the measurement of biomarkers that indicate oxidative stress levels.
It is our mission to be of service to the scientific community by developing fast, accurate, useful, and cost-effective
oxidative stress related products so that the basic and applied research in this field can progress at a faster pace.
|Company name: Japan Institute for the Control of Aging (JaICA), Nikken SEIL Co., Ltd.
Representative: Seiichi Ohi (president)
Street address: 710-1 Haruoka, Fukuroi, Shizuoka, 437-0122 Japan
Phone: +81-538-49-0125 / FAX: +81-538-49-1267
The Japan Institute for the Control of Aging has conducted research into control of aging since its
foundation under the doctrine of contributing health promotion. As a result, the institute
succeeded in developing a DNA oxidative damage measuring kit, thus taking the lead for this field.
The institute now sells many products related to oxidative stress, and such products are utilized in
the fields of medicine, pharmacy, biochemistry, food sciences, etc. The institute also performs
assay services utilizing its unique technologies. Preventive medicine and anti-aging are receiving
increased attention with the advancement of aging society. In these areas, our Institute will
contribute to realizing a healthy, long-lived society by developing and supplying research products.
|History of JaICA
1985 Founded the Japan Institute for the Control of Aging.
1986 Organized seminars on comfortable aging.
1990 Released oxidized DNA, 8-OHdG ELISA kit.
1991 Have funded Genox Corporation in Minnesota.
1995 Released oxidized lipid, anti 4-HNE
1996 Have opened Genox Baltimore office.
1998 Initiate the assay service as a registered sanitation inspection institute.
2000 Registered as a satellite center of the Trace Element Institute for UNESCO.
2003 Released oxidized lipid, HEL ELISA kit.
2008 Have patents for antioxidant assay kit PAO.
2012 Released oxidized protein Dityrosine ELISA kit.
2012 Have started radiation testing service.
2013 Received ISO/IEC 17025 certification (radioactivity testing).
2018 Have opened Genox LosAngeles office.
|Business of the institute
Develop, manufacture and sell biomarkers used for measuring oxidative stress and antioxidants.
Assay services using biomarkers, such as urine and blood sampling tests and food antioxidant assays.
The Japan Institute for the Control of Aging is engaged in the kit reagent business and assay service business.
In the kit reagent business, our Institute develops, manufactures,
and sells research reagents used for measuring oxidative stress
markers. In addition, our Institute's monoclonal antibodies and
ELISA kits used for detecting products of oxidative damage
caused by reactive oxygen species are highly evaluated by
customers worldwide. The 8-OHdG Check (8-OHdG ELISA kit),
the main product of the Institute, was awarded the Ikeda Special
Prize of the Innovation Grand Prix in 1999 and a prize from the
Minister of Science and Technology Agency in 2000.
In the assay service business, we conduct sample testing on urine and blood and perform antioxidant
assays on foods based on the products we have developed and the analysis skills we have accumulated
over many years. Interest in preventive medicine, anti-aging, and functional foods has increased in recent
years. As a result, there have been growing number of requests from hospitals, universities, research
institutes, food manufacturers, and medicine manufacturers all over Japan to analyze oxidative stress
markers, aging-related hormones, and minerals.
Download brochure (PDF: 1.7MB)
Download product catalog (PDF: 1.5MB)
|Certification (Radioactivity testing service at JaICA)
ISO/IEC 17025: 2005
ISO/IEC 17025 is the most important standard for calibration and testing laboratories, which has many commonalities with
ISO 9001: 2000 standard, but is more specific in requirements for competence.
Certification Body: Japan Accreditation Board (JAB)
Certification Number: RTL03750
Standard: JIS Q 17025:2005 (ISO/IEC 17025:2005)
Scope of Certification: Radioactivity testing services (I-131, Cs-134, and Cs-137)
for food products and beverages
|Recent publications and presentations
|[Poster] 17th Society for Free Radical Research International: SFRRI-2014 (Kyoto, 3/23-26, 2014) |
|[Poster] Society of Toxicology 52nd annual meeting (San Antonio, TX, U.S.A. 3/10-14, 2013) |
|[Poster] 35th Annual meeting of the Molecular Biology Society of Japan: MBSJ (Fukuoka, 12/11-14, 2012) |
|[Poster] 17th Annual meeting of Japan Society of Food Factors (Shizuoka, 11/10-11, 2012) |
|[Poster] 4th Slovenian Congress of Clinical Chemistry with International Participation and
20th International Symposium of Slovenian Association for Clinical Chemistry and Croatian Society of Medical Biochemists.
(Portoroz, Slovenia, September 28-29, 2012) |
|[Poster] 12th Annual meeting of Japan Society of Anti-Aging Medicine (Yokohama, 6/22-24, 2012) |
|[Poster] 65th Annual meeting of Society for Free Radical Research Japan: SFRR-J (Tokushima, 6/7-8, 2012) |
|K Sakai, S Kino, A Masuda, M Takeuchi, T Ochi,
J Osredkar, B Rejc, K Gersak, N Ramarathnam, Y Kato;|
Determination of HEL (Hexanoyl-Lysine Adduct): A Novel Biomarker for Omega-6 PUFA Oxidation.
Lipid Hydroperoxide-Derived Modification of Biomolecules: Subcellular Biochemistry 77,p61-72(2014)
|Barregard L, et. al.;
Human and Methodological Sources of Variability in the Measurement of Urinary 8-Oxo-7,8-dihydro-2'-deoxyguanosine.
Antioxid Redox Signal (2013)|
|XY Luo, T Takahara, J Hou, K Kawai, T Sugiyama, K Tsukada,
M Takemoto, M Takeuchi, L Zhong, XK Li;
Theaflavin attenuates ischemia-reperfusion injury in a mouse fatty liver model.
Biochem Biophys Res Commun 417,p287-293(2012)|
|Sun J, Sugiyama A, Masuda A, Ochi T, Takeuchi M.
Expressions of protein oxidation markers, dityrosine and advanced oxidation protein products in acetaminophen-induced
liver injury in rats. J Vet Med Sci. 73(9), p1185-1190 (2011)|
|Sugiyama A, Fujita Y, Kobayashi T, Ryu M, Suzuki Y, Masuda A, Ochi T, Takeuchi M
.Effect of protein malnutrition on the skin epidermis of hairless mice.
J Vet Med Sci. 73(6), p831-835 (2011)|
|Sugiyama A, Sun J, Nishinohara M, Fujita Y, Masuda A, Ochi T, Takeuchi M:
Expressions of lipid oxidation markers, N(epsiron)-hexanoyl lysine and acrolein in cisplatin-induced nephrotoxicity
in rats. J Vet Med Sci. 73(6), p821-826 (2011)|
|Kimoto Y, Sugiyama A, Nishinohara M, Asano A, Masuda A, Ochi T, Takeuchi M.
Expressions of protein oxidation markers, dityrosine and advanced oxidation protein products in Cisplatin-induced
nephrotoxicity in rats. J Vet Med Sci. 73(3), p403-407 (2011)|
|Sakai K, et.al. Analysis of antioxidant activities in vegetable oils and fat soluble
vitamins and biofactors by the PAO-SO method.
D Armstrong Ed., Adv Protocol Oxidative Stress II 594, p241-250 (2010)|
|Contact information of JaICA
| TEL: +81-538-49-0125, FAX: +81-538-49-1267 (Supported language: Japanese/English)
Web site: http://www.jaica.com
NOTICE: We have been receiving huge number of spam mails and DDos attacks, and e-mails from some domains
may be rejected by our server. If your e-mails can't be sent correctly, please try to contact us by FAX.
Thank you very much for your understanding.
|Address and how to reach JaICA
| Address: Haruoka 710-1, Fukuroi, Shizuoka, 437-0122 Japan
1) From Tokyo: Kakegawa sta. by Shinkansen(Kodama), and transfer to JR local train to reach Fukuroi sta.(total 2.5 hours).
2) From Nagoya/Osaka: Hamamatsu sta. by Shinkansen(Kodama), and transfer to JR local train (total 1.5 / 3 hours).
About 20 minutes drive by taxi from Fukuroi sta. of JR local train.
|About usage/links to our web site/citation/exemption
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But even if some damage would causedby such faults, we will be exempt from responsibility.
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