Type of
marker |
Item |
Spec. |
Applications |
Remark |
| Urine |
Serum |
Cells |
DNA
oxidation
marker |
8-OHdG
New 8-OHdG Check ELISA
(Code. KOG-200SE), ELISA: 450nm, 96 wells
Highly Sensitive 8-OHdG Check ELISA
(Code. KOG-HS10E), ELISA: 450nm, 96 wells
Anti 8-OHdG monoclonal antibody (N45.1)
(Code: MOG-020P / MOG-100P)
|
Assay range:
0.5 - 200 ng/mL
Assay range:
0.125-10 ng/mL
20 µg /
100 µg of IgG
|
OK
OK
-
|
OK
OK
-
|
-
OK
OK
|
Suitable for urine and animal serum. Assay time: 2.5 hours.(KOG-200SE)
Suitable for human serum,tissue and cultured cells. Assay time: overnight +1.5 hours(KOG-HS10E)
Highly specific to 8-OHdG. Low cross reactivity to oxidized RNA(8-OHGua/8-OHG).
|
Anti Thymidine Glycol (TG) antibody
(Code: MTG-100P) Clone 2E8 |
100 µg of IgG |
- |
- |
OK |
DNA-specific oxidative stress marker. Specific to TG in DNA polymer. |
Lipid
oxidation
marker |
HEL (13HPODE-Lys adduct)
Hexanoyl-Lysine (HEL) ELISA kit
(Code: KHL-700E), ELISA: 450nm, 96 wells
Anti Hexanoyl-Lysine (HEL) antibody
(Code: MHL-021P) Clone 5F12
|
Assay range:
2 - 700 nmol/L
20 µg of IgG
|
OK
-
|
OK
-
|
OK
OK
|
Nε-Hexanoyl-Lysine (HEL) is derived from 13-HPODE, and is a novel biomarker for early stage oxidation of
n:6 polyunsaturated fatty acid. Detectable in urine, serum, tissue and cultured cells.
|
4-HNE
Anti 4-HNE monoclonal antibody (HNEJ2)
(Code: MHN-020P / MHN-100P) |
20 µg /
100 µg of IgG |
-
|
-
|
OK
|
4-hydroxy-2-nonenal (4-HNE) is one of the major oxidized products of fatty acids.
Specific to 4-HNE-modified proteins. |
MDA
Anti MDA monoclonal antibody
(Code: MMD-030n) Clone 1F83
Malondialdehyde assay kit (TBARS)
(Code: KMD-008W) Colorimetric: 400-700nm scan
|
30 µg of IgG
Assay range:
0.08 - 10 µmol/L
|
-
OK
|
-
OK
|
OK
OK
|
Specific to Malondialdehyde(MDA)-protein adducts such as dihydropyridine-lysine (DHP-lysine).
By utilizing 3rd derivative analysis, more reliable results than that by traditional TBARS assay.
|
Isoprostane
Urinary isoprostane ELISA
(Code: KIP-050) ELISA: 450nm, 96wells
Serum isoprostane ELISA
(Code: KIP-001W) ELISA: 450nm, 96wells
|
Assay range:
0.05 - 100 ng/mL
Assay range:
0.05 - 10 ng/mL
|
OK
-
|
-
OK
|
-
OK
|
15-Isoprostane F2t
(also known as 8-epi-PGF2α or 8-iso-PGF2α) is produced by peroxidation of lipoproteins.
For serum or tissue samples, purification by C18/Silica Sep-Pak will be needed. |
Anti Acrolein (ACR) antibody
(Code: MAR-020n) Clone 5F6 |
20 µg of IgG |
- |
- |
OK |
Specific to ACR modified proteins: formyl-dehydropiperidino-lysine (FDP-lysine). |
Anti 4-hydroxy-2-hexenal (4-HHE) antibody
(Code: MHH-030n) Clone HHE53 |
30 µg of IgG |
- |
- |
OK |
Specific to HHE-histidine Michael adduct (HHE-His). |
Anti Crotonaldehyde (CRA) antibody
(Code: MCA-030n) Clone 82D3 |
30 µg of IgG |
- |
- |
OK |
Specific to CRA-protein aduucts. |
Anti Methylglyoxal (MG) antibody
(Code: MMG-030n) Clone 3C |
30 µg of IgG |
- |
- |
OK |
Specific to MG-protein adduct (argpyrimidine). |
Anti 7-ketocholesterol (7-KC) antibody
(Code: MKC-020n) Clone 35A |
20 µg of IgG |
- |
- |
OK |
Biomarker of cholesterol oxidation. Applicable for frozen tissue only. |
Mitochondria
Lipid peroxide probe (mitochondria)
(Code: PLP-466J) |
5 µg x3
|
-
|
-
|
OK
|
Fluorescence probe for lipid peroxides specific to mitochondia. Suitable for cultured cells. |
Lipid peroxide probe (DPPP)
(Code: PLP-350J) |
10 mg |
- |
OK |
OK |
Fluorescence probe for lipid peroxides. For HPLC application. |
Protein
oxidation
marker |
Dityrosine (Tyr dimer)
Dityrosine (DT) ELISA
(Code: KDT-010E), ELISA: 450nm, 96 wells
Anti Dityrosine (DT) antibody
(Code: MDT-020P) Clone 1C3
|
Assay range:
0.05-12 µmol/L
20 µg of IgG
|
OK
-
|
OK
-
|
-
OK
|
New biomarker specific for protein oxidation. Assay time: overnight + 1.5hours.
|
Anti Dibromo-Tyrosine (DiBrY) antibody
(Code: MBY-020P) Clone 3A5 |
20 µg of IgG |
- |
- |
OK |
Inflammation-related protein oxidation marker. |
NO-modification
Anti Nitrotryptophan (NW) antibody
(Code: MNW-020P) Clone 117C |
20 µg of IgG
|
-
|
-
|
OK
|
A novel nitrosative stress marker derived from peroxynitrite and tryptophan. |
Nitrotyrosine ELISA
(Code: KNT-002W) 96 wells |
2 - 1500 nmol/L |
- |
OK |
Δ |
|
dROMs
BAP
Assay |
Free Radical Evaluator System
Free Carrio Duo System(Code: SDR-001Q)
dROMs Assay(Code: SDR-040Q) 40 assay
BAP Assay(Code: SDR-050Q) 40 assay
|
Assay range:
40 - 1000 UCARR
50 - 6000 µmol/mL
|
-
-
|
OK
OK
|
-
-
|
Photometer system designed for rapid assessment of
d-ROMs (oxidation status) and the BAP (antioxidant status) |
Anti-
oxidant
assay |
Total Antioxidant
Test kit for Potential Antioxidant(PAO)
(Code: KPA-050) Colorimetric: 480-492 nm, 96 wells
TAC Peroxyl assay, 96 wells
(Code: KPR-005W) Luminescence
|
Assay range:
21.9- 4378 µmol/L
Assay range:
0.5～30 µmol/mL
|
-
-
|
OK
OK
|
OK
OK
|
Total antioxidant assay for serum, foods and beverages. Can detect both hydrophobic and hydrophilic antioxidants.
KPR-005W can detect peroxyl radicals(ROO·) scavenging activity. |
GSH
Total Glutathione assay kit
(Code: KGS-419J) Colorimetric: 405-415 nm, 100 tests |
Assay range:
5-100 µmol/L |
-
|
-
|
OK
|
The most abundant antioxidant in living cells. Applicable to a variety of samples such as plant tissues and bacteria. |
Enzyme
assay |
SOD
SOD activity assay kit (WST-1 method)
(Code: KSD-311J) Colorimetric: 450 nm, 500 tests
SOD activity assay kit (Hematoxylin method)
(Code: KSD-005W) Colorimetric: 560 nm, 96 wells
Cu/Zn-SOD ELISA (Human SOD1)
(Code: KSE-040W) ELISA: 450 nm, 96 wells
Mn-SOD ELISA (Human SOD2)
(Code: KSG-025W) ELISA: 450 nm, 96 wells
ec-SOD ELISA (Human SOD3)
(Code: KSF-002W) ELISA: 450 nm, 96 wells
|
Assay range:
5-60 U/mL
Assay range:
0.04 - 5 ng/mL
Assay range:
25 - ng/mL
Assay range:
2 - 168 ng/mL
|
-
-
-
-
-
|
OK
Eryth-
rocyte
OK
-
-
|
OK
OK
OK
OK
OK
|
Can be applied to all animals, plants and bacteria.
SOD1 is mainly located in erythrocytes and tissue cells. Trace concentration of SOD1 would be detected in serum.
Mn-SOD(SOD2) is detectable in Mitochondria.
|
CAT
Catalase activity assay kit
(Code: KCA-003W) UV: 240 nm, 96 wells |
Assay range:
6-150 U/mL |
-
|
Eryth-
rocyte |
OK
|
|
MPO activity assay kit
(Code: KMP-008W) Colorimetric: 412 nm
96 microplate assays or 30 cubette assays |
Assay range:
8- 400 U/mL |
- |
OK |
OK |
|
GSH metabolism
Glutathion Peroxidase (GPx) assay kit 192 wells
(Code: KGX-005W) Colorimetric: 340 nm
Glutathion Reductase (GR) assay kit 192 wells
(Code: KGR-015W) Colorimetric: 340 nm
|
Assay range:
5-60 mU/mL
Assay range:
1.5-20 mU/mL
|
-
-
|
Blood
Blood
|
OK
OK
|
|
Redox
regulation
markers |
Thioredoxin
Thioredoxin I ELISA (human) 96 wells
(Code: KRX-004W) ELISA: 450 nm
|
Assay range:
0.4- 25 ng/mL |
-
|
OK
|
Δ
|
|
Thioredoxin reductase I ELISA (human) 96 wells
(Code: KRR-004W) ELISA: 450 nm |
Assay range:
0.4- 25 ng/mL |
- |
OK |
Δ |
|
Peroxiredoxin I ELISA (human) 96 wells
(Code: KPX-005W) ELISA: 450 nm |
Assay range:
0.5 - 32 ng/mL |
- |
OK |
Δ |
|
Peroxiredoxin III ELISA (human) 96 wells
(Code: KPZ-002W) ELISA: 450 nm |
Assay range:
2 - 32 ng/mL |
- |
OK |
Δ |
|
Trace
elements
assay |
Fe
Iron assay kit (Ferrozine) 100 tests
(Code: CFE-005) Colorimetric: 540-580 nm
Iron assay kit (Nitroso-PSAP) 100 tests
(Code: CFE-010) Colorimetric: 740-760 nm
UIBC assay kit (Bathophenanthroline) 100 tests
(Code: CBC-800) Colorimetric: 540-550 nm
|
Assay range:
5-1,000 µg/dL
Assay range:
10-1,000 µg/dL
Assay range:
10-800 µg/dL
|
OK
OK
-
|
OK
OK
OK
|
OK
OK
-
|
Iron (Fe) is an important pro-oxidant factor which produce hydroxyl radical by fenton reaction.
CFE-005 and CFE-010 can be also applied to extractes from animal tissue, plants and hair samples.
Detection of unsaturated iron binding capacity(UIBC). Species independent. |
Cu
Copper assay kit (3,5-DiBr-PAESA) 100 tests
(Code: CCU-400) Colorimetric: 570-590 nm |
Assay range:
3-400 µg/dL |
OK
|
OK
|
OK
|
Can detect total (free and ceruloplasmin - bond) copper. Also applicable to extractes from tissues, plants and hair. |
Zn
Zink assay kit (5-Br-PAPS)
(Code: CZN-001) Colorimetric: 550-580 nm |
Assay range:
4-1,000 µg/dL |
OK
|
OK
|
OK
|
Can detect total (free and protein - bond) zinc. Also applicable to extractes from tissues, plants and hair. |
Ca
Calcium assay kit (Chlorophosphonazo III)
(Code: CCA-020) Colorimetric: 680-700 nm, 200 tests
Calcium assay kit (o-Cresolphtalein-Complexone)
(Code: CCA-030) Colorimetric: 560-590 nm, 200 tests
|
Assay range:
0.05-20 mg/dL
Assay range:
0.2-30 mg/dL
|
OK
OK
|
OK
OK
|
OK
OK
|
Applicable to serum, plasma, urine, saliva, extracts from tissues, plants, hair and bone samples. Avoid EDTA containing samples. |
Mg
Magnesium assay kit (Xyridil Blue-I) 100 tests
(Code: CMG-035) Colorimetric: 660 nm |
Assay range:
0.05-3.5 mg/dL |
OK
|
OK
|
OK
|
Applicable to serum, plasma, urine, saliva, extracts from tissues, plants and hair.
May be interfared by EDTA, haemolysis, anticoagulants and potassium. |
